Cukierman-Yaffe T et al. Hypoglycemia and Incident cognitive Dysfunction: A Post Hoc Analysis From the ORIGIN Trial. Diabetes Care 2018;41:2370-2376. doi: 10.2337/dc18-1131 L’association entre hypoglycémies sévères et démence ou dysfonction cognitive chez les adultes diabétiques de type 2 d’âge moyen ou âgés est controversée avec des études épidémiologiques en faveur [1-3], et des études […]
Li et al. An Automated Grading System for Detection of Vision-Threatening Referable Diabetic Retinopathy on the Basis of Color Fundus Photographs. Diabetes Care 2018; 41:2509–2516. doi: 10.2337/dc18-0147 La rétinopathie diabétique (RD) est la complication microangiopathique la plus fréquente du diabète. Elle touche approximativement 34,6% de la population diabétique, et c’est une des principales causes […]
Lu J et al. Association of time in range, as assessed by continuous glucose monitoring, with diabetic retinopathy in type 2 diabetes. Diabetes Care 2018;41:2370-2376. doi: 10.2337/dc18-1131 La mesure continue du glucose interstitiel (CGM – continuous glucose monitoring) permet l’amélioration de l’équilibre métabolique des patients qui l’utilisent en temps réel, sans majoration du risque […]
Cardoso CRL, et al. Prognostic impact of the ankle-brachial index on the development of micro- and macrovascular complications in individuals with type 2 diabetes: the Rio de Janeiro Type 2 Diabetes Cohort Study. Diabetologia 2018 Nov;61(11):2266-2276. doi: 10.1007/s00125-018-4709-9 L’index de pression systolique (IPS) est la méthode la plus largement utilisée pour détecter une maladie […]
D’Aiuto F, et al. Systemic effects of periodontitis treatment in patients with type 2 diabetes: a 12 month, single-centre, investigator-masked, randomised trial. Lancet Diabetes Endocrinol 2018 Nov;6(12):954-965. doi: 10.1016/S2213-8587(18)30038-X. [Epub ahead of print]. L’inflammation est un élément perturbateur du contrôle glycémique dans le diabète et est directement impliquée dans l’athérosclérose et la maladie rénale […]
Ji et al. Genome-wide and abdominal MRI-imaging data provides evidence that a genetically determined favourable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease and hypertension. Diabetes. 2018 Oct 23. pii: db180708. doi: 10.2337/db18-0708 De nombreuses études ont montré que l’excès de poids seul, évalué […]
Frias JP et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes : a randomised, placebo-controlled and active comparator-controlled phase 2 trial. Lancet. 2018 Oct 3. pii: S0140-6736(18)32260-8. doi: 10.1016/S0140-6736(18)32260-8. [Epub ahead of print]. La place des agonistes du récepteur du GLP-1 (glucagon-like peptide-1) […]
Burden of Urological Complications in Men and Women With Long-standing Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Cohort. Diabetes Care 2018 Oct; 41(10): 2170-2177. doi: 10.2337/dc18-0255 Peu d’études se sont penchées sur les affections urologiques associées au diabète. La dysfonction érectile (DE) est la plus connue, […]
Zhou JJ et al. Glycemic Variation and Cardiovascular Risk in the Veterans Affairs Diabetes Trial. Diabetes Care. 2018 Oct 41:2187-2194. pii: S0140-6736(18)32260-8. doi: 10.2337/dc18-0548 Les recommandations actuelles concernant la prise en charge du diabète de type 2 (DT2) sont basées sur les mesures de la glycémie et le dosage d’HbA1c pour évaluer l’équilibre glycémique […]
Game et al. LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial. Lancet Diabetes Endocrinol. 2018 Sep 19. pii: S2213-8587(18)30240-7. doi: 10.1016/S2213-8587(18)30240-7 Les maux perforants plantaires sont une cause majeure d’invalidité, et de stress chez nos patients diabétiques. La guérison est souvent […]
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