Ziegler AG, et al. Yield of a Public Health Screening of Children for Islet Autoantibodies in Bavaria, Germany. JAMA. 2020;323:339-351. doi : 10.1001/jama.2019.21565 Le diabète de type 1 (DT1) reste une maladie relativement rare (environ 13 cas pour 100 000 habitants/an en France) ne justifiant pas actuellement de dépistage systématique chez l’enfant. Un dépistage […]
Begaye B et al. Impaired Metabolic Flexibility to High-fat Overfeeding Predicts Future Weight Gain in Healthy Adults. Diabetes 2020;69: 181-192. doi : 10.2337/db19-0719 Des apports alimentaires excédant la dépense énergétique de façon prolongée, conduisent à une prise de poids. Cependant, malgré des conditions d’études strictement contrôlées, certains individus prennent plus de poids que d’autres […]
Ghouse J et al. Effect of Diabetes Duration on the Relationship Between Glycaemic Control and Risk of Death in Older Adults With Type 2 Diabetes. Diabetes Obesity and Metabolism 2020 Feb;22 (2):231-42. doi : 10.1111/dom.13891 Le diabète de type 2 (DT2) est extrêmement fréquent après 65 ans et augmente le risque de décès prématuré, […]
Farrell et al. A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes: a proof-of-concept study. Diabetologia 2020. [Epub ahead of print]. doi : 10.1007/s00125-019-05076-5 Les hypoglycémies sévères sont un effet indésirable de l‘insulinothérapie au cours du diabète, associées à une morbi-mortalité plus […]
Ruiz de Adana MS, et al. Randomized Study to Evaluate the Impact of Telemedicine Care in Patients With Type 1 Diabetes With Multiple Doses of Insulin and Suboptimal HbA1c in Andalusia (Spain): PLATEDIAN Study. Diabetes Care. 2020;43:337-342. doi: 10.2337/dc19-0739 Avec le développement technologique des outils d’information et de communication, la télémédecine est devenue, ou […]
Brouwer A et al. Sleep and HbA1c in patients with Type 2 Diabetes: Which sleep characteristics matter most? Diabetes Care 2020; 43:235-243. doi: 10.2337/dc19-0550 Le sommeil, régulé à la fois par des facteurs neuroendocrines et comportementaux, a été identifié comme un élément modifiable de l’équilibre glycémique des patients atteints de diabète de type 2 […]
Furler J et al. Use of professional-mode flash glucose monitoring, at 3-month intervals, in adults with type 2 diabetes in general practice (GP-OSMOTIC): a pragmatic, open-label, 12-month, randomized controlled trial. Lancet Diabetes Endocrinol. 2020 Jan 8;1 (11):17-26. doi: 10.1016/S2213-8587(19)30385-7 Le contrôle glycémique est indispensable pour réduire le risque de complications et la mortalité toute […]
Wang et al. Intensive LDL cholesterol-lowering treatment beyond current recommendations for the prevention of major vascular events: a systematic review and meta-analysis of randomised trials including 327 037 participants. Lancet Diabetes Endocrinol 2020; 8: 36–49. doi: 10.1016/S2213-8587(19)30388-2 Le LDL-cholestérol (LDL-C) est un facteur de risque avéré de développement des maladies cardio-vasculaires athéromateuses. Plusieurs méta-analyses […]
Dungan K et al. Effect of beta blocker use and type on hypoglycemia risk among hospitalized insulin requiring patients. Cardiovasc Diabetol 2019;18:163. doi: 10.1186/s12933-019-0967-1 Chez les patients atteints de diabète, hospitalisés hors réanimation, les hypoglycémies (<70 mg/dL) représentent jusqu’à 5% de toutes les glycémies mesurées, et sont d’autant plus fréquentes que les patients reçoivent […]
Cannon CP et al. Evaluating the Effects of Canagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Chronic Kidney Disease According to Baseline HbA1c, Including Those with HbA1c <7%: Results From the CREDENCE Trial. Circulation. 2019;11. doi: 10.1161/CIRCULATIONAHA.119.044359 On le sait, les nouvelles classes d’antidiabétiques – inhibiteurs de SGLT2 (iSGLT2) et […]
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